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Naturdao is used to control dietary histamine and other digestive system problems :
Naturdao is used for all those cases in which these diseases or problems are due to a deficiency of the diamine oxidase enzyme in the small intestine.
Histamine is formed in foods by the action of the decarboxylase enzymes of microorganisms from the precursor amino acid L-histamine.
If the metabolic activity of the enzyme Diamine Oxidase (DAO) is reduced due to genetic, pharmacological and/or pathological factors, it does not degrade the ingested histamine, passing it into the circulation through the intestinal mucosa and causing the appearance of symptoms.
Food histamine, associated with pseudoallergic phenomena, can occur with the ingestion of foods containing histamine, such as red wine, beer, chocolate, sauerkraut, fish, and processed meats. Histaminosis is an enteric dysfunction that frequently affects the population of industrialized countries. This disorder is more common in people with low levels of intestinal histaminase, a copper-containing diamine oxidase (DAO, EC 18.104.22.168) capable of catalyzing the oxidative breakdown of histamine and producing H2O2, NH3 and imidazole acetaldehyde. Histamine sensitivity is associated with symptoms such as gastrointestinal discomfort, migraine, irritation of the nasal mucosa, pruritus and other forms of allergy. Furthermore, histamine, also known as a pro-inflammatory agent, is a risk factor for subjects suffering from inflammatory bowel diseases (IBD) and colon cancer. Furthermore, a decrease in histamine catabolism activity has been demonstrated in the colonic mucosa of patients with colonic adenomas.
There is currently no pharmaceutical treatment available to control the level of intestinal histamine. In this context, considering that intestinal DAO is the main metabolizing enzyme of ingested histamine, dietary supplements of DAO (Naturdao) administered orally have been suggested for the treatment of alimentary histamine and other dysfunctions related to altered histamine metabolism. histamine.
Naturdao has no side effects.
Naturdao is part of the category of digestive enzymes, which are natural substances that help break down food and facilitate its digestion. These enzymes are essential for the proper functioning of the digestive system, since they are involved in the breakdown of proteins, carbohydrates and fats, among other nutrients.
Regarding side effects and interactions, to date no problems related to the use of Naturdao have been described. This means that no adverse effects or undesirable reactions have been reported in people who have used it. Additionally, no negative interactions have been observed with other medications or supplements. However, it is important to remember that each person is unique and may react differently.
In relation to the DAO (Diamino Oxidase) supplement, it is important to note that due to its molecular weight, it is not absorbed into the bloodstream. Instead, it runs through the entire digestive system, playing its role in the breakdown of histamine, a substance present in many foods that can trigger unpleasant symptoms in people sensitive to it. Once it has done its job in the digestive process, the DAO supplement is eliminated from the body through excretion.
Under strict controls on allergens and pathogens, as well as highly qualified transit and stability tests, NaturDao ensures a high quality standard that does not alter its composition, thus ensuring that there are no side effects due to external agents, since the active ingredient of Legumactive® has no contraindications and/or side effects.
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