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Nocisens in detail

Atopic dermatitis is a chronic inflammatory skin disorder. It includes the appearance of dryness, irritation and an itchy sensation that causes the need to scratch the affected area, causing inflammation, injuries and infections on the skin. Nocisens® is a unique neurodermatological cream on the market designed for the care of sensitive skin that hydrates and leaves a soft texture on the skin. Suitable from 36 months. Now also in body oil.

Nocisens in detail Nocisens in detail

What is Nocisens® and what is it for?

Nocisens® is a neurodermatological cream that is used to treat atopic skin or atopic dermatitis in babies, children and adults. Nocisens® hydrates, regenerates and nourishes the skin, preventing the recurrence of breakouts.

 

 

 

 

 

NOCISENS BABY

 

Nocisens Baby

Who can benefit from Nocisens ® Baby?

Nocisens® Baby is a cream that is specifically designed for the care of delicate and atopic-prone skin of babies and children under 36 months. This formula has been created to relieve discomfort, repair and soothe the skin, especially in areas prone to irritation, itching or eczema, such as those in contact with diapers or clothing.

How does Nocisens Baby act on the skin of the little ones?

The Nocisens® range of products is distinguished by its gentle composition that is respectful of the most sensitive skin. It contains a novel ingredient, Hydroxymethoxyiodobenzyl glycolamide pelargonate, with neurodermatological properties that relieve uncomfortable sensations and contribute to restoring the epidermal barrier. In addition, the combination of fatty acids provides deep hydration, while antioxidant molecules, such as tocopherol, prevent skin deterioration due to daily aggressions.

Can Nocisens Baby be used daily?

Yes, daily use of Nocisens® Baby is recommended. This cream with a soft texture and highly moisturizing can be applied twice a day to help strengthen the sensitive skin of children and relieve skin discomfort.

Is it possible to combine Nocisens Baby with other topical products or medications?

Yes, you can use Nocisens® Baby simultaneously with other topical products or medications, such as corticosteroids or antibiotics. It is advisable to apply Nocisens® Baby first and wait for it to be absorbed before using another product.

On which parts of the body can Nocisens Baby be applied?

Nocisens® Baby can be applied to dry or sensitive areas throughout the body, including the face. However, contact with mucous membranes or open wounds should be avoided. For delicate areas such as the eyelid, it is recommended to use a cotton pad to remove excess product.

Is Nocisens Baby useful for seborrheic dermatitis?

Nocisens® Baby is effective in combating dryness and itching, so it may be beneficial for children experiencing these conditions. It is important to note that the concentrated and very hydrating texture of the cream may not be well tolerated by oily skin.

Has the effectiveness of Nocisens Baby been proven?

Studies carried out by independent companies under pediatric control have shown that Nocisens® Baby is safe and well tolerated by all skin types, and is also hypoallergenic.

Furthermore, in a test of use under pediatric control carried out in children under 46 months: 2

  • 100% of the parents surveyed after the study answered that their babies had calmer skin.

  • 100% of the parents surveyed after the study answered that their babies had more hydrated, elastic and nourished skin.

  • 95% of parents surveyed after the study stated that their babies' skin was softer and had a better appearance.

 

GRADES

  1. Tolerance study carried out by independent companies on a panel of 50 volunteers with sensitive skin.

  2. Study carried out by independent companies on a panel of 22 children with sensitive skin. The results were obtained after two weeks of use following the recommended schedule (2 times a day). 

All Prospera Buotech creams include innovative neurodermatological ingredients. These are active ingredients that exert their action on the cutaneous neurosensory system, causing annoying sensations such as itching, stinging or pain.

These ingredients are combined in Nocisens ® with other highly moisturizing ingredients that help mitigate dryness and restore skin balance. The result is hydrated, balanced skin free of sensory discomfort.

 

 

NOCISENS INTENSE

Nocisens Intense

Who is Nocisens® Intense indicated for?

If your skin is sensitive, atopic-prone, and you experience areas prone to irritation or frequent breakouts, especially when aggravated by factors such as stress, pollution or climate changes, then Nocisens® INTENSE has been formulated with you in mind.

How does Nocisens® Intense work?

The Nocisens® product line is characterized by its careful composition, especially designed for delicate skin. Its innovative formulation includes:

  1. Hydroxymethoxyiodobenzyl glycolamide pelargonate: This innovative neurodermatological ingredient acts at the sensory receptors of the epidermis, relieving uncomfortable sensations caused by dryness and dermal sensitivity. Its continued use contributes to restoring the epidermal barrier, preventing water loss and strengthening the skin's natural defenses. This component is the result of years of scientific research by the Sensory Neurobiology group of the Institute for Research, Development and Innovation in Health Biotechnology of the Miguel Hernández University of Elche.

  2. Combination of fatty acids with moisturizing action: These fatty acids not only intensely moisturize, but also provide a soft texture that favors the action of the cream in the deepest layers of the epidermis.

  3. Antioxidant molecules such as tocopherol: These molecules work to prevent oxidation and deterioration of the skin's main components due to daily aggressions, offering additional defense.

In summary, Nocisens® INTENSE is a cream that not only seeks to relieve skin discomfort, but also prevent its reappearance, while providing hydration and balance to your sensitive skin.

SCIENTIFIC REFERENCES

  1. Serafini M., et al., Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders. Journal of Medicinal Chemistry. 61 (2018) 4436-4455. https://pubs.acs.org/doi/10.1021/acs.jmedchem.8b00109 .

  2. López-González et al. Improving a Natural Compound: Design of Innovative neurocosmeceuticals for Sensitive Skin. IFSCC. Vol 23 (2018) 1; 37-44.

  3. Fernández Carvajal A et al. Metabolically deactivatable TRPV1 thermoreceptor modulators in the pharmacology of pruritus. Rev. Soc. Esp. Farmacol. Vol 18 (2020) 3: (in press). http://www.ifth.es/publicaciones-y-divulgacion/revistas/aft/

 

What is the difference between Nocisens® Intense and Nocisens® Oil?

Nocisens® INTENSE is distinguished from Nocisens® OIL by having twice the concentration of active ingredients, which gives it a more powerful action. Nocisens® INTENSE is recommended for use on more sensitive or breakout-prone areas, while Nocisens® OIL is ideal for general skin maintenance.

From what age can Nocisens® Intense be used?

Nocisens® INTENSE is formulated to be used by children from 3 years of age. For children under 3 years of age, the use of Nocisens® BABY is suggested, specifically designed for the skin of the little ones.

Can I use Nocisens® Intense daily?

Yes, daily use of Nocisens® INTENSE is recommended, applying it twice a day. This concentrated, highly moisturizing cream is designed to strengthen dry skin and combat skin discomfort.

Can I combine Nocisens® Intense with other topical products or drugs?

Yes, Nocisens® INTENSE can be used simultaneously with other topical products or drugs, such as corticosteroids or antibiotics. It is advisable to apply Nocisens® INTENSE and wait for it to be absorbed before applying another product.

On which parts of the body can I use Nocisens® Intense?

You can apply Nocisens® INTENSE to dry or sensitive areas all over the body, including the face. However, contact with mucous membranes or open wounds should be avoided. For delicate areas such as the eyelid, it is recommended to use a cotton pad to remove excess product.

Is Nocisens® Intense useful for treating seborrheic dermatitis?

Nocisens® INTENSE is highly effective in combating dryness and itching, making it a beneficial option for those suffering from these conditions. It is important to note that the concentrated and very hydrating texture of the cream may not be well tolerated by oily skin.

Has the effectiveness of Nocisens® Intense been proven?

Studies carried out by independent companies have confirmed the effectiveness and tolerance of Nocisens® products on all skin types, including the most sensitive in children. According to the results, 100% of users stated that Nocisens® leaves their skin softer and calmer, 95% thought that it hydrates and nourishes the skin, 85% found their skin more flexible and elastic, and 85% experienced comfort after using Nocisens®.

 

GRADES

  1. Studies carried out by independent companies to measure the effectiveness and tolerance of Nocisens ® objectively in volunteers. Measurement of skin capacitance with the Corneometer ® and measurement of transepidermal water loss with the Tewameter ® . Both measurements were carried out on day 0 (before using the product) and after 28 days using it under professional control.

  2. The trials have been carried out by an independent company on a panel of 22 people of both sexes between 19 and 65 years old.

 

NOCISENS OIL

Nocisens Oil

What is Nocisens® Oil?

Nocisens® OIL is a neurodermatological oil designed to nourish, regenerate and hydrate sensitive or atopic-prone skin. This product is formulated for body care for the entire family and is recommended for application 1 or 2 times a day. It is suitable for use from 3 months of age.

Would Nocisens® Oil be beneficial for me?

If you are looking for a specific product for the daily care of sensitive and atopic-prone skin, Nocisens® OIL may be the right option for you. It is absorbed quickly, helping to relieve uncomfortable sensations and keeping your skin hydrated and balanced.

What is Nocisens® Oil used for?

The combination of avocado and oat oils, along with neurodermatological ingredients, acts on three essential levels for sensitive skin:

  1. Nourish and regenerate: Avocado oil penetrates deeply, nourishing the different layers of the skin and improving its regeneration properties.

  2. Strengthen the barrier function and hydrate: Oat oil stimulates the synthesis of ceramides, promoting cell regeneration and increasing natural hydration, thus restoring balance and strengthening the barrier function.

  3. Relieve uncomfortable sensations: Neurodermatological ingredients contribute to reestablishing sensory balance, helping to reduce the uncomfortable sensations typical of sensitive or atopic-prone skin.

What is the difference between Nocisens® Oil and Nocisens® Intense?

Nocisens® INTENSE contains double the concentration of active ingredients compared to Nocisens® OIL, which gives it a more powerful action. It is suggested to use Nocisens® OIL for general skin maintenance and Nocisens® INTENSE for more sensitive or breakout-prone areas.

From what age can Nocisens® Oil be used?

Nocisens® OIL is safe for the entire family, including children from 3 months of age. Its safety and effectiveness have been evaluated under pediatric and dermatological control.

Can I apply Nocisens® Oil daily?

Yes, it is recommended to use Nocisens® OIL 1 to 2 times a day. Its progressive effect allows you to recover and maintain the balance and healthy appearance of the skin in a few days of use.

Can I combine Nocisens® Oil with other topical or pharmaceutical products?

Yes, Nocisens® OIL can be used simultaneously with other topical products or medications, such as corticosteroids or antibiotics. It is advisable to apply Nocisens® OIL and wait for it to be absorbed before applying another product.

Can I use Nocisens® Oil in the shower?

It is recommended to use Nocisens® OIL on dry skin, since the absorption and, therefore, the effectiveness of the product, may be lower on wet skin.

Has the effectiveness of Nocisens® Oil been proven?

Studies carried out by independent companies have confirmed that the products of the Nocisens® line are well tolerated on all skin types, even the sensitive skin of children. Results indicate that 100% of users experienced smoother, calmer skin, 95% stated that Nocisens® hydrates and nourishes the skin, 85% noted greater flexibility and elasticity, and 85% felt comfort after using Nocisens®.

GRADES

  1. Studies carried out by independent companies to measure the effectiveness and tolerance of Nocisens ® objectively in volunteers. Measurement of skin capacitance with the Corneometer ® and measurement of transepidermal water loss with the Tewameter ® . Both measurements were carried out on day 0 (before using the product) and after 28 days using it under professional control.

  2. The trials have been carried out by an independent company on a panel of 22 people of both sexes between 19 and 65 years old.


SCIENTIFIC REFERENCES

  1. Serafini M., et al., Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders. Journal of Medicinal Chemistry. 61 (2018) 4436-4455. https://pubs.acs.org/doi/10.1021/acs.jmedchem.8b00109 .

  2. López-González et al. Improving a Natural Compound: Design of Innovative neurocosmeceuticals for Sensitive Skin. IFSCC. Vol 23 (2018) 1; 37-44.

  3. Fernández Carvajal A et al. Metabolically deactivatable TRPV1 thermoreceptor modulators in the pharmacology of pruritus. Rev. Soc. Esp. Farmacol. Vol 18 (2020) 3: (in press). http://www.ifth.es/publicaciones-y-divulgacion/revistas/aft/


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